Sprecher
Matthew Pasek
(University of South Florida, School of Geoscience)
Beschreibung
The formation of organophosphates is a critical step in the origin of life on the earth. While several routes to phosphorylation have been identified many rely on soluble phosphates. I present here a new approach to phosphorylation that relies upon reduced oxidation state phosphorus compounds (phosphite and its dimer, pyrophosphite), reacting with ammonia to produce P-N compounds. These P-N compounds are capable of phosphorylating several nucleosides with ease, and suggest an expanded inventory of phosphorylation on the early earth.
