Philipp Holliger, PhD,
Program Leader / Head of PNAC division
MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK
email: ph1@mrc-lmb.cam.ac.uk
A critical event in the origin of life is thought to have been the emergence of an RNA molecule capable of self-replication as well as mutation, and hence evolution towards ever more...
The cell membrane organizes and protects life in its role as a responsive interface and selective barrier. Lipids, the fatty amphiphilic molecules that make up the membrane bilayer, are central to membrane function. But we have no idea why cells tightly regulate the synthesis of hundreds of membrane lipids when one lipid is enough to form a bilayer. What is all that complexity good for? What...