One of the most fascinating questions arising from studies of our planet, and of the wider Universe, is the origin of life on Earth. There are two main hypotheses describing the source of the organic compounds that could have served as the basis of life: the formation of prebiotic molecules under the conditions assumed to have existed on the primitive Earth; and their formation in the Solar...
RNA replication can occur inside lipid vesicles driven by activated nucleotides entering through the membrane. We study this using computational models. A metabolism is an autocatalytic reaction that maintains itself in a non-equilibrium state inside a cell while the outside environment remains inactive. We call this requirement inside-outside stability. We demonstrate that some forms of...