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Nick Lane (UCL, UK)17.06.22, 08:30
The idea that life can act as a guide to its own origins has gained in strength in recent years with experimental work demonstrating that a biomimetic protometabolism starting from H2 and CO2 is indeed favoured in the absence of genes and enzymes. I will present some of our own recent work, both modelling and experimental, which shows that (i) CO2 fixation can be driven by a pH gradient across...
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Frances Westall (CNRS, FR)17.06.22, 08:55
After 70 years of experimentation, we still have not reconstructed the origin of life – but in the meantime many interesting experiments have been conducted, some more promising than others. One of the constraints may be that the topic is approached from too much of an organic chemistry point of view and not enough from the environmental side. Happily, there is budding awareness of the...
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Christof Mast (LMU Munich, DE)17.06.22, 09:20
The complexity of solution compositions in natural OOL scenarios is in stark contrast to the often specifc initial requirements of reactions in prebiotic chemistry or molecular evolution. Failure to meet these conditions, as is often the case in natural environments, leads quite often to a multitude of undesired side products with low or vanishing yields of the target products. Heat fluxes...
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